Journal Information
Journal ID (publisher-id): BM
Journal ID (nlm-ta): Biochem Med (Zagreb)
Title: Biochemia Medica
Abbreviated Title: Biochem. Med. (Zagreb)
ISSN (print): 1330-0962
ISSN (electronic): 1846-7482
Publisher: Croatian Society of Medical Biochemistry and Laboratory Medicine
Article Information
Copyright statement: ©Croatian Society of Medical Biochemistry and Laboratory Medicine.
Copyright: 2022, Croatian Society of Medical Biochemistry
License (open-access):
This is an Open Access article distributed under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Date received: 22 September 2022
Date accepted: 31 October 2022
Publication date (electronic): 15 December 2022
Publication date (print): 15 February 2023
Volume: 33
Issue: 1
Electronic Location Identifier: 010101
Publisher ID: bm-33-1-010101
DOI: 10.11613/BM.2023.010101
On determining the sensitivity and specificity of a new diagnostic test through comparing its results against a non-gold-standard test
Farrokh Habibzadeh[*]
Author notes:
[*] Corresponding author: Farrokh.Habibzadeh@gmail.com
Diagnostic tests are important clinical tools. To assess the sensitivity and specificity of a new test, its results should be compared against a gold standard. However, the gold-standard test is not always available. Herein, I show that we can compare the new test against a well-established diagnostic test (not a gold-standard test, but with known sensitivity and specificity) and compute the sensitivity and specificity of the new test if we would have compared it against the gold-standard test. The technique presented is useful for situations where the gold standard is not readily available.
Keywords: biostatistics; diagnostic tests; prevalence; sensitivity and specificity